Description
Etylen, CAS 74-85-1
乙烯
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Etylen, CAS 74-85-1
🔒 演示模式 — 此商品不出售。
合法物质。dhscientific.com 是 MOL-GOD 平台的演示 — 我们不出售任何商品，也不处理订单。被禁止的物质会依据法规基准在此自动拦截（例如可参见七氯）。
化学概述: EthyleneMolGod_OVERVIEW_1
| 分子式 | C2H4 |
| 分子量 | 28.05 g/mol |
| 熔点 | -169.11 °C |
| 沸点 | -103.72 °C |
| LogP（亲脂性） | 1.2 |
| IUPAC名称 | ethene |
| SMILES | C=C |
| InChIKey | VGGSQFUCUMXWEO-UHFFFAOYSA-N |
同义词: ETHYLENE · Ethene · Acetene · Elayl · Olefiant gas
数据来源： PubChem (NLM/NIH)
最后更新： 2026-11-10
物理化学性质
快速参考
化学式：
C2H4
分子量：
28.05 g/mol
CAS号：
74-85-1
外观：
Colorless gas
气味：
Sweet
气味：
Sweet
详细性质
| 属性 | 值 | 单位 | 条件 | 来源 |
|---|---|---|---|---|
| 熔点（mp） | -169.11 °C (-272.4 °F) | 1 atm | ||
| 沸点（bp） | -103.72 °C (-154.7 °F) | 1 atm | ||
| 闪点 | -100.00 °C (-148 °F) | closed cup | ||
| 水溶性 | 0.131 | g/L | 25 °C (77 °F) |
🔬 高级属性
化学标识符
SMILES:
C=C 数据来源： PubChem, NIST Chemistry WebBook, CRC Handbook of Chemistry and Physics (103rd ed.)
最后更新： 2026-07-11
📡 光谱学 — CAS 74-85-1MolGod_SPECHUB_MAIN
理化性质（数据库） 6 字段 MolGod评分：无来源
| 属性 | 值 | 单位 | 条件 | 来源 |
|---|---|---|---|---|
| 熔点 | -169.11 | °C | 1 atm | |
| 沸点 | -103.72 | °C | 760 mmHg | |
| 水溶性 | 0.131 | g/L | 25°C | |
| 闪点 | -100.00 | °C | closed cup | |
| 自燃温度 | 450.00 | °C | in air | |
| logP (辛醇/水) | 1.200 | — | 25°C |
📚 科学参考文献（芝加哥作者-日期格式） (12 来源)
- Haynes, William M., ed. 2024. CRC Handbook of Chemistry and Physics. 105th ed. Boca Raton: CRC Press/Taylor & Francis. ISBN 978-1-032-55554-4. ↗
- National Institute of Standards and Technology. 2024. "NIST Chemistry WebBook, SRD 69." Gaithersburg, MD: NIST. Accessed 2025-01-01. ↗
- Yaws, Carl L. 2014. The Yaws Handbook of Physical Properties for Hydrocarbons and Chemicals. 2nd ed. Oxford: Gulf Professional Publishing.
- PubChem. 2024. "PubChem Compound Database." National Library of Medicine, National Institutes of Health. Accessed 2025-01-01. ↗
- Marrero, J., and R. Gani. 2001. "Group-Contribution Based Estimation of Pure Component Properties." Fluid Phase Equilibria 183–184: 183–208. ↗
- Joback, K. G., and R. C. Reid. 1987. "Estimation of Pure-Component Properties from Group-Contributions." Chemical Engineering Communications 57 (1–6): 233–243. ↗
- Sangster, J. 1997. Octanol-Water Partition Coefficients: Fundamentals and Physical Chemistry. Chichester: Wiley. ISBN 978-0-471-97397-3.
- Mannhold, Raimund, and Han van de Waterbeemd. 2001. "Substructure and Whole Molecule Approaches for Calculating Log P." Journal of Computer-Aided Molecular Design 15 (4): 337–354. ↗
- Perrin, Ditlev D., Boyd Dempsey, and E. P. Serjeant. 1981. pKa Prediction for Organic Acids and Bases. London: Chapman and Hall. ISBN 0-412-21090-5.
- Constantinou, Leonidas, and Rafiqul Gani. 1994. "New Group Contribution Method for Estimating Properties of Pure Compounds." AIChE Journal 40 (10): 1697–1710. ↗
- Ertl, Peter, Bernhard Rohde, and Paul Selzer. 2000. "Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties." Journal of Medicinal Chemistry 43 (20): 3714–3717. ↗
🛡️ 安全 — CAS 74-85-1MolGod_SAFEHUB_MAIN
数据限制说明。 本页安全信息仅供参考，不能替代完整的安全数据表（SDS）。使用产品前，请查阅制造商当前的安全数据表以及GHS/CLP指南。CLP分类适用于纯散装物质，不适用于商业制剂。
GHS/CLP分类——(EC) No 1272/2008法规 + UN GHS Rev. 9 (2021)。
⚠️ 危险 (Danger)
🚨 危险说明（H）
- H220 — 极其易燃气体
- H336 — 可引起昏睡或眩晕
🛡 防范说明（P）
- P203 — 使用前取得、阅读并遵循所有安全说明书。
✓ 根据CLP法规(EC) 1272/2008附件VI的统一分类（官方、具有约束力的分类）。 索引号：601-010-00-3。
参考文献（芝加哥格式）： European Chemicals Agency. "ethylene, Index No. 601-010-00-3." In Table 3 of Annex VI to Regulation (EC) No 1272/2008 (CLP Regulation), 23rd Adaptation to Technical Progress. Helsinki: European Chemicals Agency, 2026. https://echa.europa.eu/information-on-chemicals/annex-vi-to-clp.
⚠ IARC — 组 3:
对人类致癌性无法分类（经IARC评估）.
(IARC/WHO对致癌性证据的独立评估 — 补充上述CLP分类。)
参考文献（芝加哥格式）： IARC. 2026. IARC Monographs on the Identification of Carcinogenic Hazards to Humans: CAS 74-85-1. Lyon, France: International Agency for Research on Cancer, World Health Organization. https://monographs.iarc.who.int/list-of-classifications/. (Accessed 2026-11-12.)
来自本地MOL-GOD列表（快照）的分类 — 未与当前IARC列表核实。 验证
翻译：CLP 法规 (EC) 1272/2008，附件 III 和 IV。数据：PubChem/NLM。
📚 综合科学参考文献 — Chicago Author-Date 10 来源
从所有Safety Hub选项卡收集的参考文献。CAS号： 74-85-1 ·
PubChem ↗
- Parlament Europejski i Rada UE. 2008. "Rozporządzenie (WE) nr 1272/2008 w sprawie klasyfikacji, oznakowania i pakowania substancji (CLP)." Dz.Urz. UE L 353. [↗] GHS，法规
- United Nations Economic Commission for Europe (UNECE). 2021. "Globally Harmonized System of Classification and Labelling of Chemicals (GHS), Ninth Revised Edition." United Nations, Geneva. [↗] GHS
- Goldfrank, Lewis R., Robert S. Hoffman, Mary Ann Howland, et al.. 2019. "Goldfrank's Toxicologic Emergencies, 11th ed.." McGraw-Hill Education, New York. ISBN 978-1-25-985961-8. Pierwsza pomoc, Toksykologia
- National Institute for Occupational Safety and Health (NIOSH). 2023. "NIOSH Pocket Guide to Chemical Hazards (DHHS Publ. 2005-149)." U.S. Department of Health and Human Services / CDC, Cincinnati, OH. [↗] Pierwsza pomoc, PPE, Toksykologia
- European Committee for Standardization (CEN). 2016. "EN 374-1:2016 — Protective gloves against dangerous chemicals and micro-organisms." CEN, Brussels. [↗] PPE
- UNECE. 2023. "European Agreement Concerning the International Carriage of Dangerous Goods by Road (ADR 2025)." United Nations, Geneva. [↗] Utylizacja, Regulacje
- National Fire Protection Association (NFPA). 2022. "NFPA 400 — Hazardous Materials Code." NFPA, Quincy, MA. [↗] Magazynowanie
- Urben, P.G. (ed.). 2017. "Bretherick's Handbook of Reactive Chemical Hazards, 8th ed.." Butterworth-Heinemann / Elsevier, Oxford. [↗] Magazynowanie
- Ministerstwo Klimatu i Środowiska RP. 2023. "Baza danych o produktach i opakowaniach oraz o gospodarce odpadami (BDO)." Ministerstwo Klimatu i Środowiska, Warszawa. [↗] Utylizacja
- International Agency for Research on Cancer (IARC / WHO). 2024. "IARC Monographs on the Identification of Carcinogenic Hazards to Humans — List of Classifications." WHO, Lyon. [↗] Toksykologia
具有自身参考文献的选项卡（紧急情况、个人防护装备、储存、废物）在其各自章节中包含额外的书目条目。
分析统计（t检验·RSD·Grubbs·Q-Dixon） ICH Q2
粘贴一系列重复测量结果（CSV或每行一个数字）。计算器将计算平均值、标准差和95%置信区间，并检测异常值（Grubbs + Dixon Q）。
分隔符：逗号、空格、制表符、换行。至少3个测量值。
📐 统计公式
x̄ = Σxᵢ / n— 算术平均值s² = Σ(xᵢ - x̄)² / (n-1)— 样本方差s = √s²— 标准差RSD% = (s / x̄) × 100%— 相对标准差CI₉₅ = x̄ ± t(0.05, n-1) × s / √n— Student's tG = |xᵢ - x̄| / s— Grubbs检验Q = |xsuspect - xnearest| / |xmax - xmin|— Dixon Q-test
来源：ICH Q2(R2) 分析方法验证 · ICH PDF ↗
🔧 HPLC故障排除——决策树 6 常见问题
12种最常见HPLC问题的诊断及决策树（每个问题5个步骤）。 来源： Snyder/Kirkland/Dolan 3rd ed. Chapter 17 + LCGC LC Troubleshooting columns 1989-2024.
宽峰 medium
症状： 色谱图上所有峰都比预期宽（半峰宽 > 2倍正常值）
🔍 诊断树：
-
1. 检查是所有峰变宽还是只有部分峰
→ 是： 所有峰→仪器问题（色谱柱或系统）
→ 否： 仅部分峰→化学问题（特定分析物与色谱柱的相互作用） -
2. 更换测试柱——问题是否消失？
→ 是： 色谱柱已耗尽——填料损坏，前几毫米有空隙。更换。
→ 否： 液相色谱系统问题 -
3. 检查死体积——进样环、连接件、检测器
→ 是： 对于4.6 mm色谱柱，进样环 > 100 µL或连接松动→更换卡套，缩短管路
→ 否： 继续诊断 -
4. 温度测试：将色谱柱从25°C升至40°C
→ 是： 峰变窄→传质动力学过慢（升高温度）
→ 否： Continue -
5. 检查流速与该色谱柱的最佳范德姆特值
→ 是： 4.6mm/5µm的最佳流速为1.0 mL/min，2.1mm/3µm的最佳流速为0.4 mL/min
→ 否： Continue
⚠️ 常见原因：
- 色谱柱已耗尽（无保护柱时超过2000次进样）
- 系统死体积 > 100 µL（错误的进样环、长管路、卡套松动）
- 温度过低（传质动力学）
- 流速超出范德姆特最佳值
- 样品溶剂比流动相A更强
✓ 修复方法：
- ✓ 更换色谱柱（当>2000次进样时）
- ✓ 检查所有连接——管路尽可能短
- ✓ 将色谱柱温度升至40°C（如果物质稳定）
- ✓ 将流速降至van Deemter最佳值
- ✓ 将样品溶解在流动相A中（而非纯有机相）
峰拖尾（拖尾因子T > 1.5） high
症状： 峰在晚洗脱侧有延伸的“拖尾”（根据USP，不对称度T = b/a > 1.5）
🔍 诊断树：
-
1. 物质是否含有碱性基团（氨基、吡啶）？
→ 是： 是 → 硅醇相互作用！向流动相A中添加0.1% TFA或5-10 mM TEA。
→ 否： Continue -
2. 检查流动相pH与物质pKa的关系
→ 是： pH = pKa ± 1 → 部分电离，峰分裂。使pH远离pKa ≥ 2个单位。
→ 否： Continue -
3. 检查色谱柱使用时间（>1500次进样？）
→ 是： 是 → 硅醇暴露（柱流失）。更换为具有更高封端度的色谱柱（XTerra、Symmetry）。
→ 否： Continue -
4. 样品是否含有金属（来自玻璃小瓶的Fe、Cu）？
→ 是： 是 → 使用II型无色小瓶或PFA小瓶。向样品中添加0.1mM EDTA。
→ 否： Continue
⚠️ 常见原因：
- 硅醇相互作用（碱性分析物 + 硅胶游离硅醇）
- pH处于分析物pKa边界（峰分裂）
- 旧色谱柱（柱流失，高硅醇活性）
- 样品中的金属（螯合 → 拖尾）
- 色谱柱过载（4.6mm色谱柱上>50 µg）
✓ 修复方法：
- ✓ 向流动相A中加入0.1% TFA（UV）或0.1%甲酸（LC-MS）
- ✓ 选择高纯度封端的色谱柱：Waters XBridge BEH、Phenomenex Kinetex
- ✓ 在pH值距离pKa ≥ 2个单位的条件下操作
- ✓ 向样品中加入0.1mM EDTA（螯合Fe/Cu）
- ✓ 对于4.6 mm色谱柱，将进样体积减少至≤ 20 µL
基线漂移 medium
症状： 基线在>5分钟内系统性上升或下降
🔍 诊断树：
-
1. 是否使用梯度（B%增加）？
→ 是： 是 → 流动相A与B在检测波长下吸收不同。溶剂更换导致UV截止波长变化。检查有机相UV吸光度百分比。
→ 否： 继续（等度） -
2. 检查色谱柱温度——是否稳定在±0.5°C？
→ 是： 是（稳定）→ 继续
→ 否： 不稳定 → 开启柱温箱（>25°C受控） -
3. 测试：关闭自动进样器，仅运行泵+色谱柱+检测器
→ 是： 漂移消失 → 自动进样器污染（清洁针头、隔垫）
→ 否： Continue -
4. 检查灯的使用时间（UV用D2灯）
→ 是： 是（>1500小时）→ 更换灯
→ 否： Continue
⚠️ 常见原因：
- 梯度洗脱，流动相UV截止值不同
- 色谱柱温度不稳定
- 自动进样器针头/隔垫污染
- UV灯老化（>1500h）
- 检测器流通池污染
- 色谱柱未平衡（<10个柱体积）
✓ 修复方法：
- ✓ 用100% A预平衡色谱柱10-15个柱体积
- ✓ 开启色谱柱恒温箱，温度30-40°C稳定
- ✓ 用50:50乙腈-水溶液清洗检测器流通池
- ✓ 如果D2灯使用时间>1500小时，请更换
- ✓ 使用基线扣除（Chromeleon、Empower原生功能）
无峰/丢失峰 critical
症状： 预期分析物峰未出现在色谱图上
🔍 诊断树：
-
1. 进样是否实际发生？
→ 是： 检查自动进样器日志、泵压力（进样时应下降）
→ 否： 自动进样器问题→检查定量环、进样针、样品瓶中的样品 -
2. 样品是否在样品瓶中（体积正确，未蒸发）？
→ 是： Continue
→ 否： 无样品——重新移液 -
3. 样品稳定性——制备时间是否超过24小时？
→ 是： 是→降解。重新制备新鲜样品。
→ 否： Continue -
4. 检查检测波长与物质的λmax是否匹配
→ 是： 检测波长与λmax不匹配→无信号。扫描DAD 200-400nm。
→ 否： Continue -
5. 测试：进样纯标准品（已知浓度，新鲜）
→ 是： 标准品出峰→样品问题（基质、衍生化）
→ 否： 标准品也无峰→系统问题（色谱柱、流动相、梯度）
⚠️ 常见原因：
- 样品未从样品瓶中抽取（自动进样器故障）
- 样品降解（超过24小时，pH/温度/光照）
- 检测波长错误
- 流动相错误（例如忘记加TFA）
- 色谱柱接反/固定相错误
- 物质在死时间（V0）洗脱→无保留，不可见
✓ 修复方法：
- ✓ 严格按照协议重新制备新鲜样品
- ✓ 紫外-可见DAD扫描200-400nm并搜索λmax
- ✓ 检查流动相组成——是否添加了TFA？
- ✓ 测试色谱柱反向（小心！）
- ✓ 对于保留时间<1分钟——降低B比例，用甲醇代替乙腈
- ✓ 检查wp_molgod_hplc_methods中的“expected_rt”表
压力过高 critical
症状： 泵压力>色谱柱最大压力的80%或系统因高压错误停机
🔍 诊断树：
-
1. 检查色谱柱是否连接正确（箭头方向）
→ 是： OK
→ 否： 色谱柱接反→将其翻转（切勿反向安装运行） -
2. 测试：从系统中移除色谱柱，仅运行泵+检测器
→ 是： 压力降至 <50 bar → 色谱柱问题（堵塞）
→ 否： 压力保持高位 → 在线过滤器堵塞，烧结滤片污染 -
3. 检查预柱过滤器（在线烧结滤片）
→ 是： 污染且变棕色 → 更换
→ 否： Continue -
4. 用 50:50 ACN:H2O 反向冲洗（不带色谱柱）——问题消失？
→ 是： 颗粒卡在第一毫米处——冲洗 30 分钟可能恢复
→ 否： 更换色谱柱
⚠️ 常见原因：
- 在线过滤器（烧结滤片）被颗粒堵塞
- 缓冲盐析（高 %B 时沉淀）
- 样品含有悬浮物（进样前用 0.22 µm 过滤）
- 色谱柱堵塞（柱床压实）
- 梯度含缓冲液相 + 高有机相 → 盐沉淀
✓ 修复方法：
- ✓ 进样前务必用0.22 µm PVDF过滤样品
- ✓ 每100次进样（或压力升高>20%时）更换在线过滤器
- ✓ 不要使用>20mM磷酸盐缓冲液+>70%乙腈（盐会析出）
- ✓ 用50:50乙腈:水反向冲洗色谱柱30分钟（如果制造商允许）
- ✓ 使用4×3mm预柱保护主色谱柱
鬼峰 high
症状： 色谱图上校准中不存在的无法解释的峰
🔍 诊断树：
-
1. 测试：空白进样（纯样品溶剂）
→ 是： 出现鬼峰 → 系统或洗脱液污染
→ 否： 仅与样品一起出现 → 基质 -
2. 鬼峰是否随梯度增大（在高 %B 下洗脱）？
→ 是： 是 → 色谱柱过载或前一次运行中的强保留物质
→ 否： 与梯度无关 → 自动进样器残留 -
3. Increase carryover wash (between injections)
→ 是： 有帮助 → 残留是原因。使用更强的清洗程序。
→ 否： Continue -
4. 纯水进样——是否有峰？
→ 是： 是 → 水源污染（来自 DI 系统的有机物）
→ 否： Continue
⚠️ 常见原因：
- 自动进样器针/定量环中的残留
- 洗脱液污染（即使是 HPLC 级）
- 前一次运行中的强保留组分
- 样品瓶中的塑料（邻苯二甲酸酯、来自瓶盖的 PEG）
- 纯化不充分的去离子水
✓ 修复方法：
- ✓ 加强清洗程序：100% B → 100% A → 50:50（3个循环）
- ✓ 校准前进行强清洗：100% DMSO或100%甲醇
- ✓ 如有疑问，用0.22 µm PTFE过滤洗脱液
- ✓ 使用琥珀色玻璃瓶和聚四氟乙烯内衬盖盛装样品
- ✓ 定期进行梯度升至100% B并持续10分钟（清洗）
📚 科学参考文献（芝加哥作者-日期格式）——点击展开
- Snyder, Lloyd R., Joseph J. Kirkland, and John W. Dolan. 2010. Introduction to Modern Liquid Chromatography. 3rd ed. John Wiley & Sons. Chapter 17 (Troubleshooting) pp. 559-616. ISBN 978-0-470-16754-0. https://doi.org/10.1002/9780470508183 [link ↗]
- Dolan, John W.. 2014. LC Troubleshooting (monthly column 1989-2024). LCGC North America. [link ↗] — John Dolan 35-letnia seria miesięcznych artykułów problemowych
- Kromidas, Stavros. 2017. HPLC Made to Measure: A Practical Handbook for Optimization. 2nd ed. Wiley-VCH. ISBN 978-3-527-31377-1. — Praktyczny przewodnik problem-solving dla labs analitycznych
- Dolan, John W.. 2013. When to Modify Method Conditions. 192-199. [link ↗] — Decision flow for changing flow rate / temperature / %B vs swapping columns.
- Dong, Michael W.. 2019. HPLC and UHPLC for Practicing Scientists. 2nd ed. Wiley. ISBN 978-1-119-31378-3. https://doi.org/10.1002/9781119313793 [link ↗] — Chapter 9 covers troubleshooting modern UHPLC systems (sub-2 µm particles).
- Meyer, Veronika R.. 2010. Practical High-Performance Liquid Chromatography. 5th ed. Wiley. ISBN 978-0-470-68218-0. — Solid step-by-step problem isolation chapter (eluents, columns, instruments).
- Snyder, L. R., J. J. Kirkland, and J. L. Glajch. 1997. Practical HPLC Method Development. 2nd ed. Wiley. ISBN 978-0-471-00703-6. — Method-development companion volume with troubleshooting cross-refs.
- Carr, Peter W.. 2009. The new physical chemistry of HPLC. 1764-1772. https://doi.org/10.1016/j.chroma.2008.11.094 [link ↗] — Theoretical basis for diagnosing efficiency losses (mass-transfer, eddy diffusion).
- Heyden, Yvan Vander, et al.. 2009. Robustness of pharmaceutical liquid chromatographic methods. 2120-2129. https://doi.org/10.1016/j.jchromb.2008.10.052 [link ↗] — How to diagnose method failures vs. system failures (Plackett-Burman).
- Engelhardt, Heinz. 2014. 100 Years of Chromatography. 2nd ed. Wiley-VCH. ISBN 978-3-527-33473-5. — Historical context for ghost-peak phenomenology (silica chemistry).
- Stoll, Dwight R., and Peter W. Carr. 2017. Two-Dimensional Liquid Chromatography: A State of the Art Tutorial. 519-531. https://doi.org/10.1021/acs.analchem.6b03506 [link ↗]
- Carr, Peter W.. 2009. The new physical chemistry of HPLC. 1764-1772. https://doi.org/10.1016/j.chroma.2008.11.094 [link ↗]
- Wu, Naijun, and Anton M. Clausen. 2007. Fundamental and practical aspects of ultrahigh pressure liquid chromatography for fast separations. 1167-1182. https://doi.org/10.1002/jssc.200700026 [link ↗]
- Engelhardt, Heinz. 2014. 100 Years of Chromatography. 2nd ed. Wiley-VCH. ISBN 978-3-527-33473-5.
- Vivó-Truyols, Gabriel, and Hans-Gerd Janssen. 2010. Probabilistic approach to peak deconvolution in chromatography. 8525-8531. https://doi.org/10.1021/ac101742z [link ↗]
ADMET — ADMET 性质
正在加载ADMET预测…
历史事件（CSB/EPA/Bretherick）
该数据库仅包含严重的工业和实验室事件（CSB、EPA RMP、Bretherick）。没有记录并不表示该物质是安全的——数据库不完整。
历史事件 (1)
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1989-10-23 Pasadena, Texas, USA (Phillips 66 Houston Chemical Complex, HCC) 灾难性 explosion 物质： Ethylene (high-pressure HDPE feed) (CAS 74-85-1) + Oxygen / atmospheric air ingress (CAS 7782-44-7)23 人死亡 314 人受伤Podczas konserwacji reaktora HDPE settling leg (rurociag 22") doszlo do otwarcia zaworu DEMCO w trakcie procedury maintenance. Uwolnienie ~38 ton mieszaniny etylen/izobutan/wodor stworzylo chmure gazowo-powietrzna, ktora zaplonila po ~90 sekundach (zrodlo nieustalone definitywnie). VCE o sile 2.4 ton TNT, zniszczyl HDPE complex.
根本原因： Single-block valve zamiast double-block-and-bleed. Procedury LO/TO niewlasciwe (compressed air zasilajacy aktuatory zaworow podlaczony do "open" zamiast "close" portow). Brak gas detection w okolicy reactora. Unauthorized work przy non-routine maintenance.经验教训： Double-block-and-bleed valve standard dla high-pressure reactor isolation. Kierunek pneumatic actuators musi byc fail-safe. OSHA PSM standard 29 CFR 1910.119 (1992) jest bezposrednim wynikiem tego incydentu.参考文献（芝加哥作者-日期格式）
- U.S. Department of Labor, Occupational Safety and Health Administration. 1990. The Phillips 66 Company Houston Chemical Complex Explosion and Fire. Washington, DC: OSHA.
- Atherton, John, and Frederic Gil. 2008. Incidents That Define Process Safety. Hoboken, NJ: Wiley-AIChE.
- Khan, Faisal I., and S. A. Abbasi. 1999. "Major Accidents in Process Industries and an Analysis of Causes and Consequences." Journal of Loss Prevention in the Process Industries 12 (5): 361-378.
📚 事件数据来源
- U.S. Chemical Safety and Hazard Investigation Board (CSB). 2024. "CSB Incident Investigation Reports." Washington, DC: CSB. 🔗
- U.S. EPA / NOAA. 2024. "CAMEO Chemicals Database." Washington, DC: U.S. Environmental Protection Agency. 🔗
- BARPI (French Bureau for Analysis of Industrial Risks and Pollutions). 2024. "ARIA Database of Industrial Accident Reports." Saint-Denis: BARPI/DGPR. 🔗
- U.S. OSHA. 2024. "OSHA Accident Investigation Reports." Washington, DC: Occupational Safety and Health Administration. 🔗
- Urben, Peter G., ed. 2017. Bretherick's Handbook of Reactive Chemical Hazards. 8th ed. Oxford: Elsevier. ISBN 978-0-08-100971-2.
- Mannan, Sam, ed. 2005. Lees' Loss Prevention in the Process Industries. 3rd ed. Oxford: Elsevier. ISBN 978-0-7506-7555-0.
- Hollnagel, Erik. 2004. Barriers and Accident Prevention. Aldershot: Ashgate. ISBN 978-0-7546-2271-9.
- Kletz, Trevor A. 2003. "Lessons from Disasters — How Organizations Have No Memory and Accidents Recur." Process Safety and Environmental Protection 81 (4): 283–287. 🔗
📚 科学文献概览 — CAS 74-85-1MolGod_LITHUB_MAIN
⭐ 关键发现（科学文献） 11 出版物
🏆 CAS
74-85-1
— multi-criteria ranking (W12): 30%引用·20%近期性·20%主题·15%历史·15%开放获取.
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#1Marcin Krynski (2026) · Zenodo (CERN European Organization for Nuclear Research)重要性： 近期（2026） · open access
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#2Zhang X, Tao J, Huang Y et al. (2026) · Journal of genetics and genomics = Yi chuan xue bao重要性： 近期（2026） · 综述 · open access
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#3Zhang J, Liu Z, Farrar EJ et al. (2026) · Nature重要性： 近期（2026） · open access
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#4Chatterjee S, Rankin JA, Farrugia MA et al. (2025) · Biochemistry重要性： 近期（2025） · open access
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#5Wang R, Bowerman AF, Chen Y et al. (2025) · Journal of experimental botany重要性： 近期（2025） · open access
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#6Zhao ZA, Li YR, Lei T et al. (2025) · Scientific reports重要性： 近期（2025） · open access
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#7He K, Xu L, He Q et al. (2024) · Journal of integrative plant biology重要性： 近期（2024） · open access
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#8Irfan M, Kumar P, Datta A (2025) · Methods in molecular biology (Clifton, N.J.)重要性： 近期（2025）
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#9Dong Y, Ma H, Shen Y et al. (2025) · The Plant journal : for cell and molecular biology重要性： 近期（2025）
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#10Guo Y, Gong J, Hu R et al. (2025) · The Plant journal : for cell and molecular biology重要性： 近期（2025）
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#11Shukla D (2025) · Methods in molecular biology (Clifton, N.J.)重要性： 近期（2025）
Related products
📚 参考文献（综合书目，芝加哥作者-日期格式） 107 条目
以上折叠面板中针对CAS号74-85-1引用的所有科学来源。格式： 《芝加哥格式手册》第17版，作者-日期系统.
🗄️ 科学数据库
- NIST. 2026. NIST Chemistry WebBook: CAS 74-85-1. Gaithersburg, MD: National Institute of Standards and Technology. https://webbook.nist.gov/cgi/cbook.cgi?ID=74-85-1. (Accessed 2026-11-12.)
- AIST. 2026. Spectral Database for Organic Compounds (SDBS): CAS 74-85-1. Tsukuba, Japan: National Institute of Advanced Industrial Science and Technology. https://sdbs.db.aist.go.jp/. (Accessed 2026-11-12.)
- PubChem. 2026. PubChem Compound Summary: CAS 74-85-1. Bethesda, MD: National Center for Biotechnology Information (NCBI), National Library of Medicine. https://pubchem.ncbi.nlm.nih.gov/#query=74-85-1. (Accessed 2026-11-12.)
- ECHA. 2026. C&L Inventory and REACH Registration: CAS 74-85-1. Helsinki: European Chemicals Agency. https://echa.europa.eu/information-on-chemicals/annex-vi-to-clp. (Accessed 2026-11-12.)
📐 标准/指南
- ICH. 2026. "ICH Harmonised Guideline: CAS 74-85-1." Geneva: International Council for Harmonisation. https://database.ich.org/sites/default/files/Q1A%28R2%29%20Guideline.pdf. (Accessed 2026-11-12.)
- National Fire Protection Association (NFPA). 2024. "NFPA 30: Flammable and Combustible Liquids Code." NFPA, Quincy, MA. https://www.nfpa.org/codes-and-standards/all-codes-and-standards/list-of-codes-and-standards/detail?code=30.
- Occupational Safety and Health Administration (OSHA). 2023. "29 CFR 1910.106 — Flammable Liquids." U.S. Department of Labor, Federal Register. https://www.osha.gov/laws-regs/regulations/standardnumber/1910/1910.106.
- European Chemicals Agency (ECHA). 2024. "Annex VI to Regulation (EC) No 1272/2008 (CLP) — Harmonised Classification and Labelling." ECHA, Helsinki / Official Journal of the European Union. https://echa.europa.eu/regulations/clp/clp-classification.
- European Committee for Standardization (CEN). 2016. "EN 374-1:2016 — Protective gloves against dangerous chemicals and micro-organisms — Part 1: Terminology and performance requirements for chemical risks." CEN, Brussels. https://standards.cencenelec.eu/dyn/www/f?p=205:110:::::FSP_PROJECT,FSP_ORG_ID:38536,6080&cs=1B0DAA8B85DF42E4A2C70E5D71F0BFA32.
- European Committee for Standardization (CEN). 2001. "EN 166:2001 — Personal eye-protection — Specifications." CEN, Brussels. https://standards.cencenelec.eu/dyn/www/f?p=CEN:110:0::::FSP_PROJECT:6541&cs=1F1A4E0A78C4DB6A28DBE2E8C29D89DCF.
- European Committee for Standardization (CEN). 2009. "EN 14605:2005+A1:2009 — Protective clothing against liquid chemicals — Performance requirements for clothing with liquid-tight (Type 3) or spray-tight (Type 4) connections." CEN, Brussels. https://standards.cencenelec.eu/dyn/www/f?p=CEN:110:0::::FSP_PROJECT:21581&cs=1A04A2D3C7CC58E9E6CB58D55F7EBFB7E.
- National Institute for Occupational Safety and Health (NIOSH). 2017. "Recommendations for Chemical Protective Clothing: A Companion to the NIOSH Pocket Guide." U.S. Department of Health & Human Services / CDC. https://www.cdc.gov/niosh/ncpc/default.html.
- Occupational Safety and Health Administration (OSHA). 2011. "Personal Protective Equipment — General requirements." U.S. Department of Labor — 29 CFR 1910.132. https://www.osha.gov/laws-regs/regulations/standardnumber/1910/1910.132.
📖 书籍
- Hansen, Charles M. 2007. Hansen Solubility Parameters: A User's Handbook, 2nd ed.. Boca Raton, FL: CRC Press. https://www.routledge.com/Hansen-Solubility-Parameters-A-Users-Handbook/Hansen/p/book/9780849372483.
- Barton, Allan F. M. 1991. CRC Handbook of Solubility Parameters and Other Cohesion Parameters: 2nd ed.. Boca Raton, FL: CRC Press. https://www.routledge.com/CRC-Handbook-of-Solubility-Parameters-and-Other-Cohesion-Parameters/Barton/p/book/9780849301766.
- Connors, Kenneth A., Gordon L. Amidon, and Valentino J. Stella. 1986. Chemical Stability of Pharmaceuticals: A Handbook for Pharmacists, 2nd ed.. New York: Wiley. https://doi.org/10.1002/0471734683.
- Rumble, John R., ed. 2019. CRC Handbook of Chemistry and Physics: 100th Edition. Boca Raton, FL: CRC Press. https://hbcp.chemnetbase.com/.
- Urben, Peter G. 2017. Bretherick's Handbook of Reactive Chemical Hazards, 8th Edition. Academic Press / Elsevier, Oxford. https://www.sciencedirect.com/book/9780081010594.
📘 专著
- IARC. 2026. IARC Monographs on the Identification of Carcinogenic Hazards to Humans: CAS 74-85-1. Lyon, France: International Agency for Research on Cancer, World Health Organization. https://monographs.iarc.who.int/list-of-classifications/. (Accessed 2026-11-12.)
📄 科学文章（同行评审）
- Stefanis, Emmanuel, and Costas Panayiotou. 2008. "Prediction of Hansen Solubility Parameters with a New Group-Contribution Method." International Journal of Thermophysics 29: 568-585. https://doi.org/10.1007/s10765-008-0415-z.
- Stoll, Vincent S., and John S. Blanchard. 1990. "Buffers: Principles and Practice: In Methods in Enzymology, vol. 182." San Diego: Academic Press. https://doi.org/10.1016/0076-6879(90)82008-P.
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- European Parliament. 2008. "Regulation (EC) No 1272/2008 on Classification, Labelling and Packaging of Substances and Mixtures (CLP)." Official Journal of the European Union L 353: 1–1355.
- ECHA. 2017. "Guidance on the Compilation of Safety Data Sheets." Version 3.1. European Chemicals Agency. ECHA-17-G-01-EN. https://echa.europa.eu/documents/10162/23047722/sds_en.pdf.
- ECHA. 2022. "Restrictions Under REACH — Annex XVII." European Chemicals Agency. https://echa.europa.eu/substances-restricted-under-reach.
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- ECHA. 2020. "Understanding REACH." European Chemicals Agency. https://echa.europa.eu/regulations/reach/understanding-reach.
- U.S. OSHA. 2026. "Occupational Safety and Health Guidance: CAS 74-85-1." Washington, DC: U.S. Occupational Safety and Health Administration. https://www.osha.gov/hazwoper. (Accessed 2026-11-12.)
- National Fire Protection Association (2018) — NFPA 472: Standard for Competence of Responders to Hazardous Materials/Weapons of Mass Destruction Incidents https://www.nfpa.org/codes-and-standards/nfpa-472.
- European Union. 2026. "EUR-Lex Legal Database: CAS 74-85-1." Luxembourg: Publications Office of the European Union. https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex:32012L0018. (Accessed 2026-11-12.)
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